Mitochondria-targeted ruthenium (II) polypyridyl complexes with benzofuran group for live cell imaging
نویسندگان
چکیده
منابع مشابه
Ruthenium(II) polypyridyl complexes as carriers for DNA delivery.
Two novel water soluble ruthenium(II) complexes [Ru(bpy)(2)(bqbg)](2+) and [Ru(phen)(2)(bqbg)](2+) have been structurally characterized and their DNA condensation activity, cytotoxicity, and cellular uptake studies of DNA condensates as potential non-viral DNA carriers were evaluated.
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Tuberculosis is one of the world's deadliest infectious disease with 1.5 millions deaths annually. It is imperative to discover novel compounds with potent activity against M. tuberculosis. In this study, susceptibilities of M. smegmatis to the octahedral ruthenium(II) polypyridyl complexes, 1 {[(bpy)3Ru] (PF6)2 (bpy = 2,2'-bipyridine)}, 2 {[(phen)2Ru(dppz)](PF6)2 (phen = 1,10-phenanthroline, d...
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Substitution-inert, redox- and photo-active ruthenium(II) complexes based on 2,2',6',2''-terpyridine ligands were self-assembled into discrete supramolecular cages via coordination to palladium(II) centres and characterised by NMR, ESI-MS and X-ray crystallography.
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The synthesis and characterization of dinuclear ruthenium polypyridyl complexes based on the bridging ligands 1,3-bis-(5’-(pyridin-2’’-yl)-1’H-1’,2’,4’-triaz-3’-yl)-benzene, 1,4-bis-(5’-(pyridin-2’’-yl)-1’H-1’,2’,4’-triaz-3’-yl)-benzene, 2,5-bis-(5’-(pyridin-2’’yl)-1’H-1’,2’,4’-triaz-3’-yl)-thiophene, 2,5-bis-(5’-(pyrazin-2’’-yl)-1’H-1’,2’,4’-triaz3’-yl)-thiophene, and of their mononuclear anal...
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A first investigation into the application of a luminescent osmium(ii) bipyridine complex to live cell imaging is presented. Osmium(ii) (bis-2,2-bipyridyl)-2(4-carboxylphenyl) imidazo[4,5f][1,10]phenanthroline was prepared and conjugated to octaarginine, a cell penetrating peptide. The photophysics, cell uptake and cytotoxicity of this osmium complex conjugate were performed and compared with i...
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ژورنال
عنوان ژورنال: Journal of Inorganic Biochemistry
سال: 2016
ISSN: 0162-0134
DOI: 10.1016/j.jinorgbio.2016.02.028